|REVIEW ARTICLE: REPUBLICATION
|Year : 2017 | Volume
| Issue : 1 | Page : 32-37
The right team at the right time – Multidisciplinary approach to multi-trauma patient with orthopedic injuries
John A Bach1, John J Leskovan1, Thomas Scharschmidt2, Creagh Boulger2, Thomas J Papadimos3, Sarah Russell4, David P Bahner5, Stanislaw P. A Stawicki6
1 Department of Surgery, Division of Trauma, Critical Care, and Burn, The Ohio State University College of Medicine, Columbus, OH, USA
2 Department of Orthopaedics, The Ohio State University College of Medicine, Columbus, OH, USA
3 Department of Anesthesiology, Division of Critical Care, The Ohio State University College of Medicine, Columbus, OH; Multi-Center Trials Group, OPUS 12 Foundation Global, Bethlehem, PA, USA
4 Department of Anesthesiology, Division of Critical Care, The Ohio State University College of Medicine, Columbus, OH, USA
5 Department of Orthopaedics, The Ohio State University College of Medicine, Columbus, OH; Multi-Center Trials Group, OPUS 12 Foundation Global, Bethlehem, PA, USA
6 Department of Surgery, Division of Trauma, Critical Care, and Burn, The Ohio State University College of Medicine, Columbus, OH; MultiCenter Trials Group, OPUS 12 Foundation Global, Bethlehem, PA, USA, USA
|Date of Web Publication||10-Mar-2017|
Stanislaw P. A Stawicki
Department of Research and Innovation, St. Luke's University Health Network, EW2 Research Administration, 801 Ostrum Street, Bethlehem, PA
Source of Support: None, Conflict of Interest: None
| Abstract|| |
Integrated, multidisciplinary team approach to the multiply injured patient can help optimize care, minimize morbidity, and reduce mortality. It also provides a framework for accelerated postinjury rehabilitation course. The characteristics and potential benefits of this approach, including team dynamics and interactions, are discussed in this brief review. Emphasis is placed on synergies provided by specialty teams working together in the framework of care coordination, timing of surgical and nonsurgical interventions, and injury/physiologic considerations.
Republished with permission from: Bach JA, Leskovan JJ, Scharschmidt T, Boulger C, Papadimos TJ, Russell S, Bahner DP, Stawicki SPA. Multidisciplinary approach to multi-trauma patient with orthopedic injuries: the right team at the right time. OPUS 12 Scientist 2012;6(1):6-10.
Keywords: Multi-disciplinary collaboration, multiple injured patient, orthopedic trauma, patient care, review, team approach
|How to cite this article:|
Bach JA, Leskovan JJ, Scharschmidt T, Boulger C, Papadimos TJ, Russell S, Bahner DP, Stawicki SP. The right team at the right time – Multidisciplinary approach to multi-trauma patient with orthopedic injuries. Int J Crit Illn Inj Sci 2017;7:32-7
|How to cite this URL:|
Bach JA, Leskovan JJ, Scharschmidt T, Boulger C, Papadimos TJ, Russell S, Bahner DP, Stawicki SP. The right team at the right time – Multidisciplinary approach to multi-trauma patient with orthopedic injuries. Int J Crit Illn Inj Sci [serial online] 2017 [cited 2017 May 29];7:32-7. Available from: http://www.ijciis.org/text.asp?2017/7/1/32/201958
| Introduction|| |
Traumatic injury is the fifth leading cause of death in the United States and the sixth leading cause of death worldwide, accounting for approximately 10% of overall global mortality.,, Among younger (<45 years old) individuals, trauma is the leading cause of death., Polytrauma, or the co-existence of multiple traumatic injuries in the same victim, is present in as many as 40% of trauma admissions., Polytrauma often involves young, productive individuals and represents a substantial burden to the society, from both financial and human perspectives. The presence of multiple simultaneous injuries can lead to significant disability with decreased probability of return to productive work and thus significant economic costs.
Observed injury patterns in the highest acuity trauma victims frequently feature concurrent involvement of anatomically distant areas, hemodynamic dysfunction, multiple organ systems, and require the attention of both generalist traumatologist as well as various sub-specialty physicians. Orthopedic trauma features dominantly on the list of commonly seen injuries, and lends itself as a perfect example of the importance of the multidisciplinary approach that has reduced postinjury morbidity and mortality at its core. This manuscript reviews key aspects of the multi-disciplinary approach to the multiply injured patient with orthopedic trauma.
| Multi-Disciplinary Teams|| |
Effective diagnostic and therapeutic approaches to the multiply injured patient require the presence of well-functioning trauma systems and integrated specialty teams. The optimal approach to the multiply injured patient involves the involvement of anesthesiologists, trauma-trained surgeons, intensivists, orthopedic specialists, diagnostic and interventional radiologists, urologists, neurosurgeons, rehabilitation specialists, otolaryngologists, among many others., Fine-tuned team management, leadership, and communication skills are of critical importance. Excellent communication between physicians and teams, including awareness of important clinical pitfalls and constant vigilance on the part of all participating team members (i.e., presence of multiple cross-checks), as well as the need for centralized care planning (including multi-disciplinary patient care conferences) are crucial.
Such multidisciplinary approach begins in the prehospital setting with early responders and emergency medical service personnel. These prehospital teams initially assess, stabilize, and transport patients to the nearest institution that is capable of managing the patient. According to trauma designation from the American College of Surgeons and the regional trauma systems, patients requiring higher levels of care are transferred to trauma centers where the multiple specialties needed to deliver optimal postinjury care are available. Due to the large overall number of injured patients, appropriate triage is important since more than 90% are best served in local community hospitals. For the remaining 10% of patients who represent the severely injured requiring Level I and II trauma centers, multidisciplinary approach is essential for improving outcomes.
| Trauma Centers and Systems|| |
In the United States, specialized trauma centers receive most of the multiply injured patients with immediately life-threatening conditions. In the Major Trauma Outcome Study, nearly half of all patients had one or more musculoskeletal injuries. According to another study, 72% of emergency evaluations following motorcycle crashes resulted in orthopedic consultation, with significant proportion of patients suffering from open fractures requiring emergent orthopedic surgical intervention.
In the presence of polytrauma, it is important to prioritize injuries based on their acuity (i.e., combination of physiologic and anatomic urgency). Utilizing the multidisciplinary approach necessitates the involvement of various medical and surgical specialists, as determined by the severity and urgency of each injury, in the context of the anticipated urgency and timeline of intervention(s). Most often, such approach also relies on the presence of the central coordinating “control point” consisting of the trauma and/or the surgical intensive care team, depending on institution. Despite its seemingly chaotic nature, such an approach requires excellent coordination of care and actively engages a multitude of medical and surgical specialists including anesthesiologists, trauma surgeons, radiologists (both diagnostic and interventional), orthopedic surgeons, oral maxillofacial surgeons, vascular, and neurosurgeons, among many others.,
This approach has certain benefits in the overall care of severely injured patients. A hypothetical example of clinical collaboration between multiple specialty teams includes a hypotensive patient with a pulseless limb after an extremity fracture. In such a case, the emergency physician and the trauma surgeon must ensure that no ongoing internal or external bleeding is occurring, and if such bleeding is taking place, he or she must be ready to perform a hemostatic procedure (i.e. suture ligation of cutaneous hemorrhage, emergency laparotomy, placement of extremity tourniquet) at any time. Concurrently, a combined orthopedic and vascular surgery team needs to reestablish distal limb perfusion and perform a repair of the fracture, with the determination of whether to utilize definitive or temporary fixation depending on the injury pattern and patient physiology. In all of the intricate planning and execution of such clinical course of action, the anesthesiologist plays a crucial role. Postoperatively, the intensivist provides Intensive Care Unit (ICU) care to the patient who most likely will require significant resuscitative efforts.
This multidisciplinary approach not only involves the surgeons, but must intimately involve professional teams at multiple levels of the health-care infrastructure. This includes (but is not limited to) nursing staff, transportation staff, midlevel providers, blood bank, case managers, social workers, specialty therapists, pharmacists, and resident/fellow physicians. In many cases, these individuals are the first to respond to the patient's initial presentation or first to notice a subsequent change in clinical status. The importance of the team approach is exemplified by the fact that any delay in recognition of significant clinical events, and thus prolonged time to therapeutic intervention, may worsen outcomes., The overall outcome of severely injured patients depend on successful integration of medical, psychosocial, financial, educational, and vocational resources available across an array of specialties and various medical centers, programs, and organizations. In sections that follow, we will discuss the care of the trauma patient from a number of different specialty perspectives.
| Emergency Physician Perspective|| |
The trauma resuscitation area is a unique arena within an emergency department where multiple individuals from various subspecialties come together to form a team with a common goal of providing care to the injured trauma patient. The approach to the multiply injured patient with orthopedic trauma begins similarly to any other trauma patient and starts with the primary survey assessment of the airway, breathing, circulatory, and neurologic status (i.e., the Advanced Trauma Life Support protocol).
This evaluation constitutes a starting point in the care of an orthopedic trauma patient. The mangled extremity can be quickly assessed and temporized., Diminished or absent pulses in an injured extremity require immediate attention as early reduction and/or repositioning and immobilization can often restore blood flow and subsequently minimize disability and potentially avoid amputation. Specific injuries such as posterior knee dislocations and unstable pelvic fractures elevate concern in the emergency physician's mind for concomitant vascular injury and may require further testing such as angiography. Once pulses are confirmed and/or restored and the patient's neurologic status assessed, the patient is fully exposed to evaluate for any less obvious injuries. After completing the adjuncts to the primary survey, a secondary “head-to-toe” evaluation is performed. This includes palpation of all bony surfaces and joints for tenderness or deformity while identifying bruising, lacerations, or other signs of tissue injury. A liberal approach to imaging is taken for the multiply injured trauma patient, especially when the patient has altered sensorium secondary to head injury, alcohol, or drugs. This liberal approach stems from the fact that extremity fractures are the most commonly missed injuries in trauma patients even in the era of “pan-imaging.”,
After the primary resuscitation is complete, the secondary management of gross deformities includes splinting the injured limb. Open injuries should be covered with betadine-soaked gauze and splinted while waiting for radiographs and a formal orthopedic consultation. Open wounds are classified as Grade 1 (<1 cm), Grade 2 (1–10 cm), and Grade 3 (>10 cm). This classification system has some utility in predicting which patients are more likely to go to the operating room. Tetanus status should always be addressed and updated with traumatic open wounds. In addition to tetanus, all open fractures also should receive prophylactic antibiotics such as cefazolin or clindamycin., In addition to all these diagnostic and therapeutic interventions, the emergency traumatologists are also trained in prompt recognition of other limb-threatening phenomena such as the compartment syndrome.
In summary, the approach to orthopedic injuries begins with the prehospital recognition of a fracture and/or dislocation and appropriate temporary splinting. On arrival in the trauma resuscitation area, the splints are kept in place until the secondary survey is completed and the injuries are evaluated and imaged appropriately. In addition to immobilization, reduction, tetanus administration and antibiotics (if indicated), pain control with short-acting analgesics like fentanyl can be used until definitive treatment is decided upon. Occasionally, the emergency traumatologist may utilize conscious sedation in the appropriately monitored patient during interventions involving severe fractures or dislocations in need of anatomical re-alignment. More recently, comprehensive ultrasound-based trauma assessment and triage protocols that incorporate musculoskeletal elements were proposed in order to increase both the efficiency and the completeness of the initial clinical evaluation of the multiply injured patient.
| Orthopedic Surgeon Perspective|| |
As mentioned previously, majority of polytrauma patients will suffer skeletal injuries. The benefit of surgical stabilization of these injuries is well defined, but the timing has been controversial and continues to evolve. Thus, care in a multi-disciplinary, team-oriented fashion is crucial for optimizing patient outcomes.
Approximately a decade ago, the concept of “damage-control orthopedics” was introduced, and has been associated with improved outcomes for the multi-trauma patient., For many years, the concept of “early total care” was employed with early, emergent stabilization of all long bone fractures., The concept of “damage-control” arose from the observation that in the subgroup of patients with multiple injuries and/or thoracic trauma, early fixation was associated with a higher rate of complications and mortality. In this group of patients at the high risk of complications, the approach is for early temporary stabilization (controlling hemorrhage, managing soft tissue injury, and often external fixation of long bone fractures) followed by delayed definitive fixation after the risk of systemic complications decreases and overall physiologic picture improves. The goal is to avoid a “second hit” and thus worsening of the patient's overall condition. Identifying patients who may benefit the most from the switch from “early total care” to “damage control” requires open communication and multidisciplinary approach. Multiple scoring systems have attempted to identify these patients, but there is no single score that reliably assists in decision-making during the acute resuscitation phase.
Patients can be generally divided into four groups: Stable, borderline, unstable, and in extremis. Stable patients can be treated with immediate fixation, and unstable/in extremis patients should be treated with damage control. The borderline patient is the most difficult one to define and identify, but also exemplifies the situation in which the decision regarding the optimal course of action is most critical and the consequences of the “incorrect” decision are profound. In general, the borderline patient has multiple thoracic and abdominal injuries and is suffering from hemorrhagic shock or sequelae thereof. Such patient is probably best treated with damage control.
A few scenarios deserve special mention. Femoral fractures are generally treated with immediate fixation using an intramedullary device, but this differs in the multi-trauma population. Embolic fat from the instrumentation is known to provoke an inflammatory response in the lung, which can serve as the “second hit” in these patients. Thus consideration for external fixation, especially in the setting of bilateral femur fractures in the multiply injured patient, should be discussed. The second unique scenario is the patient with a pelvic ring injury and associated hemorrhage. Rapid clinical decisions must be made with regards to the appropriate skeletal and/or hemodynamic stabilization procedure(s) for the patient, and may include a variety of clinical approaches from pelvic binder/external fixation, to therapeutic angiography, to emergent open pelvic packing.,, These patients also require a specialized team approach to optimize outcomes.
The timing of definitive fixation of secondary injuries or conversion from external fixation to definitive fixation is also a crucial decision. Most patients treated with damage control techniques can be definitively stabilized within 1 week, but this may depend on the overall physiologic state of the patient. Days 2–4 following the injury have been defined as the time of greatest systemic inflammation and any additional unnecessary surgery should be avoided during this period.
| Anesthesiologist Perspective|| |
In all of the intricate planning and execution of such a clinical course of action, the anesthesiologist plays a crucial role. In the provision of perioperative care for the orthopedic trauma patient, the anesthesiologist/anesthesiology team intervenes at several important junctures. The first important aspect of anesthesia care is the airway. Trauma aside, the fact that greater than 35% of the United States population is obese, more than 10% of nonoperative intubations are difficult, and 20% of all critical incidents in the ICU are airway related , all combine to make appropriate and cautious planning, securing, and maintaining airway absolutely critical.
In addition, trauma could render a patient unconscious, may be associated with cervical spine injury or facial fractures, and is not infrequently complicated by blood and/or vomitus in the airway. The coexistence of these factors further corroborates the crucial nature of the anesthesiology expertise and prominent presence on the multi-disciplinary trauma team.
Adequate vascular access for infusion of intravenous fluids, blood products, medications, and for hemodynamic monitoring is of great importance. While this expertise is also shared with surgeons, the presence and assistance of anesthesiology in this area is very helpful, thereby freeing up the surgeons to focus on operative management of traumatic injuries. Most anesthesiologists are also well versed with procedures such as arterial line placement, thoracostomy and nasogastric tube insertion.
Hemodynamic and fluid management, as well as transfusion medicine are at the core of the anesthesiologist's scope of practice. The orthopedic trauma patient will benefit from, and the surgical team will be complemented by, this aspect of perioperative anesthesia expertise. The use of blood products, colloid solutions, and crystalloid solutions in the care of the injured, along with the knowledge of vasopressor, vasodilator, inotrope, and antiarrhythmic agents optimizes and adds to the success of trauma interventions.
Finally, the induction of an anesthetic with clinical vigilance during definitive surgical interventions is an important traditional role of the anesthesiologist. Choosing a regional approach, a general anesthetic, or monitored anesthesia care is an extremely important clinical decision, which should be carried out in consultation beforehand with the surgical colleagues. Furthermore, during the operative intervention, hemodynamic monitoring, with appropriate physiological and pharmacological interventions make competent, appropriate anesthesiology expertise a true necessity.
| Intensivist Perspective|| |
Postoperatively, the intensivist provides critical care support to patients who are deemed to be most likely to require significant resuscitative efforts. In the United States, the intensivist role can be currently fulfilled by specialty trained anesthesiologists, surgeons, internists, and emergency physicians., They work closely with the trauma care team providing everything from consultative input to the primary provision of critical care services. The critical care team, working closely with the trauma team, is well positioned to cover all aspects of patient care except for the surgical care of the injury.
Manipulation of the ventilator, cardiopulmonary physiology and pharmacology, transfusion medicine, resuscitation, nutrition, wound care, infectious diseases/sepsis/antibiotic administration, renal support therapy, and other aspects of critical care all fall within the purview of the intensivist. In other words, care of the dysfunction, or failure, of the central nervous, cardiopulmonary, renal (dialysis), gastrointestinal tract/liver, and hematologic systems, among others, are the part of their scope of practice. They may also apply the technologies of the pulmonary catheter, bedside ultrasonography and related methodologies, arterial blood pressure monitoring, intra-aortic balloon pump, ventricular assist devices (right, left, biventricular), and extracorporeal membrane oxygenation, to the most seriously injured patients.
The comorbidities that affect the patient's underlying health (including aging),, become a framework for the intensivist's approach to a successful intervention in the trauma patient. The intensivist is also intimately involved in and responsible for the effective intervention and coordination of consultants involved in any particular case. The intensivist is thus, in effect, a concierge, making sure interactions between the patient, family members, nurses, consultants, and the primary surgical team proceed smoothly, and that as few as possible perturbations occur in the encounters with, and care of, patients and their families.
| Conclusions|| |
In summary, interdisciplinary healthcare approach to the multiply injured patient can help optimize care, minimize morbidity and mortality, and ultimately provide a framework for accelerated postinjury rehabilitation course. Potential benefits of utilizing this approach when treating the multi-trauma patient with orthopedic injury are significant and disadvantages are few. The authors would like to emphasize the synergies provided by specialty teams working together in the context of care coordination, timing of surgical and nonsurgical interventions, and physiologic considerations.
Justifications for re-publishing this scholarly content include: (a) The phasing out of the original publication – the OPUS 12 Scientist and (b) Wider dissemination of the research outcome(s) and the associated scientific knowledge.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Søreide K. Epidemiology of major trauma. Br J Surg 2009;96:697-8.
National Center for Health Statistics (U.S.). National Hospital Discharge Survey. Hyattsville, MD.: DHHS Publication, U.S. Department of Health and Human Services, Centers for Disease Control and Prevention. 2016. p. v.
Peters S, Nicolas V, Heyer CM. Multidetector computed tomography-spectrum of blunt chest wall and lung injuries in polytraumatized patients. Clin Radiol 2010;65:333-8.
Marx JA, Hockberger RS, Walls RM, Adams J, Rosen P. Rosen's Emergency Medicine: Concepts and Clinical Practice. Philadelphia: Mosby/Elsevier; 2010.
Bonatti H, Calland JF. Trauma. Emerg Med Clin North Am 2008;26:625-48, vii.
Amin NH, Jakoi A, Katsman A, Harding SP, Tom JA, Cerynik DL. Incidence of orthopedic surgery intervention in a level I urban trauma center with motorcycle trauma. J Trauma 2011;71:948-51.
Wisler JR, Beery PR 2nd
, Steinberg SM, Stawicki SP. Competing priorities in the brain injured patient: Dealing with the unexpected. In: Agrawal A, editor. Brain Injury: Pathogenesis, Monitoring, Recovery and Management. Rijeka, Croatia: InTech; 2012. p. 341-54.
Mirza A, Ellis T. Initial management of pelvic and femoral fractures in the multiply injured patient. Crit Care Clin 2004;20:159-70.
Stawicki SP. Trends in nonoperative management of traumatic injuries: A synopsis. OPUS 12 Sci 2007;1:19-35.
Ruchholtz S, Waydhas C, Lewan U, Piepenbrink K, Stolke D, Debatin J, et al.
A multidisciplinary quality management system for the early treatment of severely injured patients: Implementation and results in two trauma centers. Intensive Care Med 2002;28:1395-404.
McSwain N, Rotondo M, Meade P, Duchesne J. A model for rural trauma care. Br J Surg 2012;99:309-14.
Browner BD, DeAngelis JP. Emergency care of musculoskeletal injuries. In: Townsend CM, Beauchamp RD, Evers M, Mattox KL, editors. Sabiston Textbook of Surgery. Ch. 21. Philadelphia, PA: WB Saunders; 2007, pp. 521-558.
Stewart BT, Lee V, Danne PD. Laparotomy for trauma in a regional centre: The effect of delay on outcome. Aust N
Z J Surg 1994;64:484-7.
Vernon DD, Furnival RA, Hansen KW, Diller EM, Bolte RG, Johnson DG, et al.
Effect of a pediatric trauma response team on emergency department treatment time and mortality of pediatric trauma victims. Pediatrics 1999;103:20-4.
Strasser DC, Uomoto JM, Smits SJ. The interdisciplinary team and polytrauma rehabilitation: Prescription for partnership. Arch Phys Med Rehabil 2008;89:179-81.
American College of Surgeons. Advanced Trauma Life Support ATLS: Student Course Manual. Chicago, IL: American College of Surgeons; 2012.
Uslu MM, Altun NS, Cila E, Atik OS. Relevance of mangled extremity severity score to compartment syndromes. Arch Orthop Trauma Surg 1995;114:229-32.
Helfet DL, Howey T, Sanders R, Johansen K. Limb salvage versus amputation. Preliminary results of the Mangled Extremity Severity Score. Clin Orthop Relat Res 1990;256:80-6.
Pallia CS, Scott RE, Chao DJ. Traumatic hip dislocation in athletes. Curr Sports Med Rep 2002;1:338-45.
Abou-Sayed H, Berger DL. Blunt lower-extremity trauma and popliteal artery injuries: Revisiting the case for selective arteriography. Arch Surg 2002;137:585-9.
Giannakopoulos GF, Saltzherr TP, Beenen LF, Reitsma JB, Bloemers FW, Goslings JC, et al.
Missed injuries during the initial assessment in a cohort of 1124 level-1 trauma patients. Injury 2012;43:1517-21.
Stawicki SP, Lindsey DE. Trauma corner – Missed traumatic injuries: A synopsis. OPUS 12 Sci 2009;3:35-43.
Zalavras CG, Patzakis MJ. Open fractures: Evaluation and management. J Am Acad Orthop Surg 2003;11:212-9.
Hoff WS, Bonadies JA, Cachecho R, Dorlac WC. East Practice Management Guidelines Work Group: Update to practice management guidelines for prophylactic antibiotic use in open fractures. J Trauma 2011;70:751-4.
Peitzman AB. The Trauma Manual: Trauma and Acute Care Surgery. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2008.
Stawicki SP, Howard JM, Pryor JP, Bahner DP, Whitmill ML, Dean AJ. Portable ultrasonography in mass casualty incidents: The CAVEAT examination. World J Orthop 2010;1:10-9.
Pape HC, Giannoudis P, Krettek C. The timing of fracture treatment in polytrauma patients: Relevance of damage control orthopedic surgery. Am J Surg 2002;183:622-9.
Pape HC, Hildebrand F, Pertschy S, Zelle B, Garapati R, Grimme K, et al.
Changes in the management of femoral shaft fractures in polytrauma patients: From early total care to damage control orthopedic surgery. J Trauma 2002;53:452-61.
Bone LB, Johnson KD, Weigelt J, Scheinberg R. Early versus delayed stabilization of femoral fractures. A prospective randomized study. J Bone Joint Surg Am 1989;71:336-40.
Bosse MJ, MacKenzie EJ, Riemer BL, Brumback RJ, McCarthy ML, Burgess AR, et al.
Adult respiratory distress syndrome, pneumonia, and mortality following thoracic injury and a femoral fracture treated either with intramedullary nailing with reaming or with a plate. A comparative study. J Bone Joint Surg Am 1997;79:799-809.
Pape HC, Auf'm'Kolk M, Paffrath T, Regel G, Sturm JA, Tscherne H. Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion – A cause of posttraumatic ARDS? J Trauma 1993;34:540-7.
Agolini SF, Shah K, Jaffe J, Newcomb J, Rhodes M, Reed JF 3rd
. Arterial embolization is a rapid and effective technique for controlling pelvic fracture hemorrhage. J Trauma 1997;43:395-9.
Gänsslen A, Giannoudis P, Pape HC. Hemorrhage in pelvic fracture: Who needs angiography? Curr Opin Crit Care 2003;9:515-23.
Pohlemann T, Culemann U, Gänsslen A, Tscherne H. Severe pelvic injury with pelvic mass hemorrhage: Determining severity of hemorrhage and clinical experience with emergency stabilization. Unfallchirurg 1996;99:734-43.
Pape HC, Schmidt RE, Rice J, van Griensven M, das Gupta R, Krettek C, et al.
Biochemical changes after trauma and skeletal surgery of the lower extremity: Quantification of the operative burden. Crit Care Med 2000;28:3441-8.
Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity in the United States, 2009-2010. NCHS Data Brief 2012;82:1-8.
Martin LD, Mhyre JM, Shanks AM, Tremper KK, Kheterpal S. 3,423 emergency tracheal intubations at a university hospital: Airway outcomes and complications. Anesthesiology 2011;114:42-8.
Needham DM, Thompson DA, Holzmueller CG, Dorman T, Lubomski LH, Wu AW, et al.
A system factors analysis of airway events from the Intensive Care Unit Safety Reporting System (ICUSRS). Crit Care Med 2004;32:2227-33.
Beckmann U, Baldwin I, Durie M, Morrison A, Shaw L. Problems associated with nursing staff shortage: An analysis of the first 3600 incident reports submitted to the Australian Incident Monitoring Study (AIMS-ICU). Anaesth Intensive Care 1998;26:396-400.
Stene JK, Grande CM. General anesthesia: Management considerations in the trauma patient. Crit Care Clin 1990;6:73-84.
Grossman MD, Portner M, Hoey BA, Stehly CD, Schwab CW, Stoltzfus J. Emergency traumatologists as partners in trauma care: The future is now. J Am Coll Surg 2009;208:503-9.
Stawicki SP, Gracias VH, Lorenzo M. Surgical critical care: From old boundaries to new frontiers. Scand J Surg 2007;96:17-25.
Evans DC, Doraiswamy VA, Prosciak MP, Silviera M, Seamon MJ, Rodriguez Funes V, et al.
Complications associated with pulmonary artery catheters: A comprehensive clinical review. Scand J Surg 2009;98:199-208.
Stawicki SP, Hoff WS, Cipolla J, deQuevedo R. Use of non-invasive esophageal echo-Doppler system in the ICU: A practical experience. J Trauma 2005;59:506-7.
Howard J, Gerckens J, Wang C, Jarvis A, Porshinsky B, Cook C, et al
. Correlation of cardiac output as measured by arterial waveform analysis versus continuous cardiac output pulmonary artery catheter. Crit Care Med 2009;37:A94.
Yuan KC, Fang JF, Chen MF. Treatment of endobronchial hemorrhage after blunt chest trauma with extracorporeal membrane oxygenation (ECMO). J Trauma 2008;65:1151-4.
Evans DC, Cook CH, Christy JM, Murphy CV, Gerlach AT, Eiferman D, et al.
Comorbidity-polypharmacy scoring facilitates outcome prediction in older trauma patients. J Am Geriatr Soc 2012;60:1465-70.
Justiniano CF, Evans DC, Cook CH, Eiferman DS, Gerlach AT, Beery PR 2nd
, et al.
Comorbidity-polypharmacy score: A novel adjunct in post-emergency department trauma triage. J Surg Res 2013;181:16-9.
Evans DC, Gerlach AT, Christy JM, Jarvis AM, Lindsey DE, Whitmill ML, et al.
Pre-injury polypharmacy as a predictor of outcomes in trauma patients. Int J Crit Illn Inj Sci 2011;1:104-9.
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Taylor JM, Gropper MA. Critical care challenges in orthopedic surgery patients. Crit Care Med 2006;34 9 Suppl: S191-9.