International Journal of Critical Illness and Injury Science

SYMPOSIUM: CRITICAL POINT OF CARE BIOMARKERS IN EMERGENCY CARE
Year
: 2014  |  Volume : 4  |  Issue : 3  |  Page : 233--237

Bedside procalcitonin and acute care


Manpreet Singh, Lakesh Anand 
 Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Chandigarh, India

Correspondence Address:
Manpreet Singh
Department of Anaesthesia and Intensive Care, Government Medical College and Hospital, Sector 32, Chandigarh
India

Procalcitonin (PCT) is a 116-amino acid protein with a sequence identical to that of the prohormone of calcitonin. Under normal conditions a specific protease cleaves all PCT to calcitonin, katacalcin and an N-terminal residue and hence in healthy individual PCT levels are either too low or undetectable. However, in severe bacterial infections or septic conditions, intact PCT is found in the blood and the concentrations of PCT may reach up to 1000 ng/ml. Point-of-care testing (POCT) is an important diagnostic tool used in various locations in the hospital, especially in intensive care unit (ICU), the operating room (OR), and emergency set-ups. Laboratory test results are often pivotal to fast decisions in majority of areas where patients are critical. Testing provides physicians with valuable knowledge about the emergency in the patients so that appropriate therapeutic interventions can be made quickly. Early detection of rising PCT levels has great significance and helps in diagnosing and managing the patients quickly. This review highlights various facts about PCT in point-of-care scenarios.


How to cite this article:
Singh M, Anand L. Bedside procalcitonin and acute care.Int J Crit Illn Inj Sci 2014;4:233-237


How to cite this URL:
Singh M, Anand L. Bedside procalcitonin and acute care. Int J Crit Illn Inj Sci [serial online] 2014 [cited 2020 Jul 7 ];4:233-237
Available from: http://www.ijciis.org/article.asp?issn=2229-5151;year=2014;volume=4;issue=3;spage=233;epage=237;aulast=Singh;type=0