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GUEST EDITORIAL |
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What is new in critical illness and injury science? Patient safety amidst chaos: Are we on the same team during emergency and critical care interventions? |
p. 135 |
Susan Moffatt-Bruce, Jennifer L Hefner, Michelle C Nguyen DOI:10.4103/2229-5151.164909 PMID:26557481 |
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SPECIAL ARTICLE |
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Regional anesthesia for management of acute pain in the intensive care unit |
p. 138 |
Mario De Pinto, Armagan Dagal, Brendan O'Donnell, Agnes Stogicza, Sheila Chiu, William Thomas Edwards DOI:10.4103/2229-5151.164917 PMID:26557482Pain is a major problem for Intensive Care Unit (ICU) patients. Despite numerous improvements it is estimated that as many as 70% of the patients experience moderate-to-severe postoperative pain during their stay in the ICU. Effective pain management means not only decreasing pain intensity, but also reducing the opioids' side effects. Minimizing nausea, vomiting, urinary retention, and sedation may indeed facilitate patient recovery and it is likely to shorten the ICU and hospital stay. Adequate postoperative and post-trauma pain management is also crucial for the achievement of effective rehabilitation. Furthermore, recent studies suggest that effective acute pain management may be helpful in reducing the development of chronic pain.When used appropriately, and in combination with other treatment modalities, regional analgesia techniques (neuraxial and peripheral nerve blocks) have the potential to reduce or eliminate the physiological stress response to surgery and trauma, decreasing the possibility of surgical complications and improving the outcomes. Also they may reduce the total amount of opioid analgesics necessary to achieve adequate pain control and the development of potentially dangerous side effects. |
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ORIGINAL ARTICLES |
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Prognosis of critical surgical patients depending on the duration of stay in the ICU |
p. 144 |
Luciano Santana-Cabrera, Josefa Delia Martin-Santana, Rosa Lorenzo-Torrent, Hugo Rodriguez Perez, Manuel Sanchez-Palacios, Juan Ramon Hernandez Hernandez DOI:10.4103/2229-5151.164919 PMID:26557483Objective: To analyze the epidemiological and prognostic differences between critical surgical patients admitted to intensive care unit (ICU) according to length of stay in the ICU.
Materials and Methods: Retrospective observational study on patients with surgical pathology admitted to ICU of a tertiary hospital, during 7 years, with a stay ≥ 5 days. The variables analyzed were age, sex, Acute Physiology and Chronic Health Evaluation II (APACHE II), duration of stay, hospital and ICU mortality, original service, reason for admission, geographical place of residence, and the use of invasive techniques such as mechanical ventilation (MV), tracheotomy, and techniques of continuous renal replacement (CRR). Two groups were defined; one with intermediate stay, the one that exceeds the average of our population (> 5 days) and another with long stay patients (> 14 days). Readmissions were excluded. Firstly, the analysis of differential characteristics of patients was performed, this was according to the duration of their stay using either a contrast equal averages when the variable contrast between the two groups was quantitative or the Chi-square test when the variable analyzed was qualitative. For both tests, the existence of significant differences between groups was considered when the significance level was less than 5%. And, secondly, a model forecast ICU survival of these patients, regardless of length of stay in ICU, using a binary logistic regression analysis was performed.
Results: Among the 540 patients analyzed, no significant differences were observed, depending on the length of stay in the ICU, except the need for invasive techniques such as MV or tracheotomy in those of longer stay (P = 0.000). However, ICU mortality was significantly higher for patients with intermediate stay (30 vs 17: 5%; P = 0.000), without observing differences in hospital mortality. ICU survival was influenced by age, APACHE II levels, admission to the ICU in a coma state, and the application of the three invasive techniques discussed.
Conclusion: Surgical patients who survive in the ICU, regardless of the length of their stay in it, have the same odds of hospital survival. Found as predictors of mortality in ICU APACHE II, age, admission in a coma state, and application of invasive techniques. |
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Can enteral antibiotics be used to treat pneumonia in the surgical intensive care unit? A clinical outcomes and cost comparison |
p. 149 |
Kathryn A Elofson, Rachel C Forbes, Anthony T Gerlach DOI:10.4103/2229-5151.164922 PMID:26557484Background: Controlling healthcare costs without compromising patient care is a focus given recent healthcare changes in the United States. The purpose of this study was to assess clinical improvement in surgical intensive care unit (SICU) patients initiated on or transitioned to enteral antibiotics compared to those who solely receive intravenous (IV) antibiotic therapy for treatment of bacterial pneumonia.
Materials and Methods: This retrospective cohort study included patients with a positive quantitative respiratory culture being treated for bacterial pneumonia in a SICU from 1/1/09 to 3/31/11. Two distinct patient groups were identified: Those treated with IV antibiotics exclusively (IV) and those either initiated on or transitioned to enteral antibiotics within 4 days of antibiotic initiation (PO). The primary endpoint of clinical improvement was assessed on day of antibiotic discontinuation.
Results: A total of 647 patients were evaluated; 124 met inclusion criteria (30 patients PO group and 94 IV group). There was no difference in clinical improvement (86.7 PO vs 72.3% IV, P = 0.14) or recurrence (10 PO vs. 12.8% IV, P > 0.99) between groups. Secondary outcomes of duration of mechanical ventilation, ICU and hospital length of stay, and all-cause mortality were also similar. Antibiotic and infection-related costs were significantly decreased in the PO group ($1,042 vs $697, P = 0.04; $20,776 vs $17,381, P = 0.012, respectively).
Conclusions: SICU patients initiated on or transitioned to PO antibiotics for pneumonia had similar clinical outcomes, but significantly less infection-related and antibiotic costs compared to those receiving IV therapy. Further, prospective studies are warranted. |
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Direct (presenting primarily to trauma center) versus indirect (referred or transferred) admission of patients to the Trauma Centre of King George Medical University: One-year prospective pilot study |
p. 155 |
Vikas Verma, Girish K Singh, Santosh Kumar, Vineet Sharma, Vijaysheel Gautam, Suresh Kumar DOI:10.4103/2229-5151.164938 PMID:26557485Background: India does not have a trauma registry. There is lack of base line demographic data of trauma victims that present directly to the trauma center and those that are transferred to the trauma center.
Aim: To compare the clinical and demographic profile of directly admitted (presenting primarily to the trauma center) and referred (transferred to trauma center) patients at the trauma centre of King George Medical University.
Materials and Methods: The demographic and clinical profiles of patients admitted on thirty-three consecutive Mondays were collected and compared. In addition, the demographic data of patients admitted on Mondays and eight randomly selected Wednesdays and Saturdays were analyzed to ascertain the representativeness of the studied sample.
Results : Of the 572 patients in the study, 327 were referred and 245 were directly admitted. There was 27% mortality in the referred group and 22% mortality in the directly admitted group, the difference been statistically insignificant (P value 0.20). Patients referred from peripheral hospitals were more severely injured with a lower GCS and a higher TRISS, and had a higher proportion of multi system major trauma and severe head injury.
Conclusion: Referred admitted (transferred) patients at the KGMU trauma center are more seriously injured than the patients presenting directly. Yet there is no statistically significant difference in the overall mortality. A future study focusing on certain sub-categories of patients such as those demonstrating subdural hematoma, GCS less than 9 or ISS more than 15 may yield interesting data. |
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SYMPOSIUM - ICU & TRAUMA PROCEDURE COMPLICATIONS |
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Complications of needle thoracostomy: A comprehensive clinical review |
p. 160 |
Brian Wernick, Heidi H Hon, Ronnie N Mubang, Anthony Cipriano, Ronson Hughes, Demicha D Rankin, David C Evans, William R Burfeind, Brian A Hoey, James Cipolla, Sagar C Galwankar, Thomas J Papadimos, Stanislaw P Stawicki, Michael S Firstenberg DOI:10.4103/2229-5151.164939 PMID:26557486Needle thoracostomy (NT) is a valuable adjunct in the management of tension pneumothorax (tPTX), a life-threatening condition encountered mainly in trauma and critical care environments. Most commonly, needle thoracostomies are used in the prehospital setting and during acute trauma resuscitation to temporize the affected individuals prior to the placement of definitive tube thoracostomy (TT). Because it is both an invasive and emergent maneuver, NT can be associated with a number of potential complications, some of which may be life-threatening. Due to relatively common use of this procedure, it is important that healthcare providers are familiar, and ready to deal with, potential complications of NT. |
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Central line complications  |
p. 170 |
Craig Kornbau, Kathryn C Lee, Gwendolyn D Hughes, Michael S Firstenberg DOI:10.4103/2229-5151.164940 PMID:26557487Central venous access is a common procedure performed in many clinical settings for a variety of indications. Central lines are not without risk, and there are a multitude of complications that are associated with their placement. Complications can present in an immediate or delayed fashion and vary based on type of central venous access. Significant morbidity and mortality can result from complications related to central venous access. These complications can cause a significant healthcare burden in cost, hospital days, and patient quality of life. Advances in imaging, access technique, and medical devices have reduced and altered the types of complications encountered in clinical practice; but most complications still center around vascular injury, infection, and misplacement. Recognition and management of central line complications is important when caring for patients with vascular access, but prevention is the ultimate goal. This article discusses common and rare complications associated with central venous access, as well as techniques to recognize, manage, and prevent complications. |
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An overview of complications associated with open and percutaneous tracheostomy procedures  |
p. 179 |
Anthony Cipriano, Melissa L Mao, Heidi H Hon, Daniel Vazquez, Stanislaw P Stawicki, Richard P Sharpe, David C Evans DOI:10.4103/2229-5151.164994 PMID:26557488Tracheostomy, whether open or percutaneous, is a commonly performed procedure and is intended to provide long-term surgical airway for patients who are dependent on mechanical ventilatory support or require (for various reasons) an alternative airway conduit. Due to its invasive and physiologically critical nature, tracheostomy placement can be associated with significant morbidity and even mortality. This article provides a comprehensive overview of commonly encountered complications that may occur during and after the tracheal airway placement, including both short- and long-term postoperative morbidity. |
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Complications of bronchoscopy: A concise synopsis |
p. 189 |
David L Stahl, Kathleen M Richard, Thomas J Papadimos DOI:10.4103/2229-5151.164995 PMID:26557489Flexible and rigid bronchoscopes are used in diagnosis, therapeutics, and palliation. While their use is widespread, effective, and generally safe; there are numerous potential complications that can occur. Mechanical complications of bronchoscopy are primarily related to airway manipulations or bleeding. Systemic complications arise from the procedure itself, medication administration (primarily sedation), or patient comorbidities. Attributable mortality rates remain low at < 0.1% for fiberoptic and rigid bronchoscopy. Here we review the complications (classified as mechanical or systemic) of both rigid and flexible bronchoscopy in hope of making practitioners who are operators of these tools, and those who consult others for interventions, aware of potential problems, and pitfalls in order to enhance patient safety and comfort. |
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Laparoscopy in trauma: An overview of complications and related topics |
p. 196 |
Tammy Kindel, Nicholas Latchana, Mamta Swaroop, Umer I Chaudhry, Sabrena F Noria, Rachel L Choron, Mark J Seamon, Maggie J Lin, Melissa Mao, James Cipolla, Maher El Chaar, Dane Scantling, Niels D Martin, David C Evans, Thomas J Papadimos, Stanislaw P Stawicki DOI:10.4103/2229-5151.165004 PMID:26557490The introduction of laparoscopy has provided trauma surgeons with a valuable diagnostic and, at times, therapeutic option. The minimally invasive nature of laparoscopic surgery, combined with potentially quicker postoperative recovery, simplified wound care, as well as a growing number of viable intraoperative therapeutic modalities, presents an attractive alternative for many traumatologists when managing hemodynamically stable patients with selected penetrating and blunt traumatic abdominal injuries. At the same time, laparoscopy has its own unique complication profile. This article provides an overview of potential complications associated with diagnostic and therapeutic laparoscopy in trauma, focusing on practical aspects of identification and management of laparoscopy-related adverse events. |
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Complications of pericardiocentesis: A clinical synopsis |
p. 206 |
Rajan Kumar, Archana Sinha, Maggie J Lin, Reina Uchino, Tracy Butryn, M Shay O'Mara, Sudip Nanda, Jamshid Shirani, Stanislaw P Stawicki DOI:10.4103/2229-5151.165007 PMID:26557491Pericardiocentesis (PC) is both a diagnostic and a potentially life-saving therapeutic procedure. Currently echocardiography-guided pericardiocentesis is considered the standard clinical practice in the treatment of large pericardial effusions and cardiac tamponade. Although considered relatively safe, this invasive procedure may be associated with certain risks and potentially serious complications. This review provides a summary of pericardiocentesis and a focused overview of the potential complications of this procedure. |
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CASE REPORT |
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Colosplenic contained perforation secondary to colonic lymphoma |
p. 213 |
Andrei Radulescu, David Arrese, John A Bach DOI:10.4103/2229-5151.165008 PMID:26557492We present the case of patient with colosplenic perforation from a colonic lymphoma. He initially was diagnosed with a splenic abscess subsequently developed a contained colonic perforation, underwent surgical treatment and intraoperatively was diagnosed with lymphoma. This is a rare entity in a non-immunocompromised host and has been scarcely reported. |
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LETTERS TO THE EDITOR |
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The use of cryotherapy via bronchoscopy for removal of obstructing tracheobronchial thrombi |
p. 215 |
Meghan Iona Cook, Thomas John Papadimos DOI:10.4103/2229-5151.165009 PMID:26557493 |
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Renal leak; mechanism of hypercalciuria in short-term immobilization |
p. 216 |
Majid Malaki DOI:10.4103/2229-5151.165010 PMID:26557494 |
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Mean platelet volume a key or obstacle in clinical affairs |
p. 217 |
Majid Malaki DOI:10.4103/2229-5151.165011 PMID:26557495 |
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Hypercapnia during endoscopic saphenectomy complicating CABG |
p. 218 |
Sujatha P Bhandary, Michael Essandoh, Saraswathi Karri, Thomas J Papadimos DOI:10.4103/2229-5151.165014 PMID:26557496 |
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Catheter-related infections |
p. 219 |
Sora Yasri, Viroj Wiwanitkit DOI:10.4103/2229-5151.165016 PMID:26557497 |
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Extensive descending necrotizing mediastinitis can be managed conservatively |
p. 219 |
Vivek Chauhan, Surinder Thakur DOI:10.4103/2229-5151.165018 PMID:26557498 |
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A letter in response to impact of acetazolamide use in severe exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation |
p. 220 |
Animesh Ray DOI:10.4103/2229-5151.165020 PMID:26557499 |
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